Management of Intrahepatıc Cholestasıs of Pregnancy: Revıew of Lıterature
نویسندگان
چکیده
Intrahepatic cholestasis of pregnancy (ICP) is a pregnancy specific liver disorder characterized by maternal pruritus in the latter half of the pregnancy, raised serum bile acids and increased rates of adverse fetal outcomes. Maternal effects of ICP are mild; however, there is a clear association between ICP and higher frequency of fetal distress, preterm delivery, and sudden intrauterin fetal death. The etiology of ICP is elusive but it is likely to result from the cholestatic effects of reproductive hormones and their metabolites in genetically susceptible women. The mechanisms by which fetal complications occur is also unclear. In this article we tried to review epidemiology, clinical features, etiology, diagnosis, pharmacologic treatment and obstetric management of ICP. Abbreviations: Intrahepatic cholestasis of pregnancy (ICP), Familial intrahepatic cholestasis (PFIC), Benign Recurrent Cholestasis (BRIC), Cholic Acid (CA), Chenodeoxycholic Acid (CDCA), Ursodeoxycholic Acid (UDCA), Neonatal Respiratory Distress Syndrome (RDS), Meconium-Stained Amniotic Fluid (MSAF), Royal College of Obstetricians and Gynaecologists (RCOG), Progressive Familial İntrahepatic Cholestasis (PFIC), Contraceptive-İnduced Cholestasis (CIC), Adenosine Triphosphate-Binding Cassette, Subfamily B, Member 4 (ABCB4), Multidrug Resistance 3 (MDR3), Respiratory Distress Syndrome (RDS).
منابع مشابه
Soft Tıssue Aneurysmal Bone Cyst: A Case Report And A Revıew Of The Lıterature
Aneurysmal bone cyst (ABC) is a benign, locally aggressive tumor of long bone and vertebral bodies. Soft tissue aneurysmal bone cyst (STABC) is an extremely rare entity that has same morphology as their osseous counterparts. The aim of this study is to keep in mind STABC in differential diagnosis of some benign and malignant tumors. A 68-year-old male presented with a swelling on his right shou...
متن کاملEffectiveness of Cognitive-Behavioral Stress Management Intervention on Anxiety and Depression during Pregnancy
Background & Aims: Motherhood has been taken into account as an enjoyable and evolutionary event in women’s life, however, because of physical and mental changes; it can cause some degrees of stress and anxiety. The present study aimed to examine the effects of cognitive-behavior stress management (CBSM) training on the levels of anxiety and depression during the pregnancy. Methods: This was a ...
متن کاملConservative management of asymptomatic hepatic hydatid cyst in pregnancy: our experience in seven patients
Introduction: To present our experience about the safety of conservative management in asymptomatic and non-complicated hepatic hydatid cyst in pregnancy. Methods: Seven pregnant patients with hepatic hydatid cysts as an incidental finding in routine obstetrical ultrasonography were referred to our center during 2001 to 2008. Three patients were visited in the second and the rest i...
متن کاملSuccessful conservative management of cervical pregnancy: case report
Background: Cervical pregnancy is a rare type of ectopic pregnancy (EP) in which the pregnancy implants in the lining of the endocervical canal. It accounts for less than 1 percent of ectopic pregnancies. The cause is unknown; local pathology related to previous cervical or uterine surgery may play a role given an apparent association with a prior history of curettage or cesarean delivery. The ...
متن کامل